Meeting Program
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1:00pm - Registration
1:45pm - Welcome Addresses: Maryellen Giger (Chair of IWBI 2024) and Steven Montner (Interim Chair of Department of Radiology, University of Chicago)
2:30pm - KEYNOTE & FIRESIDE CHAT: State of Breast Cancer Screening, including realities and limitations worldwide - Olufunmilayo Olopade, MD, FACCR, OON, University of Chicago, and Benjamin O. Anderson, MD, FACS, University of Washington
Introduction: Maryellen Giger, University of Chicago, Chair
Moderator: Martin Yaffe, University of Toronto4:00pm - Break
4:30pm - Walking Tour of University of Chicago Campus
6:00pm - Welcome Reception, with heavy hors d’oeuvres
8:30pm - Adjourn
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7:30am - Registration and breakfast
8:30am - KEYNOTE: Multi-energy and Multi-modality Breast Cancer Imaging
- John A. Shepherd, PhD, University of Hawaii Cancer Center
Moderators: Maryellen Giger, University of Chicago, Chair and Karen Drukker, University of Chicago9:30am - Break
Session 1 - Contrast-enhanced DBT/Mammography
Moderator: Martin Tornai, NIH/NIBIB10:00am - Simulated image-specific microcalcification clusters and associated mass enhancement to enhance training of a deep learning model for cancer detection in contrast-enhanced mammography - Astrid Van Camp, Maastricht University
10:20am - Experimental results of the first prototype direct-indirect dual-layer flat-panel detector for contrast enhanced digital mammography and contrast enhanced digital breast tomosynthesis - Wei Zhao, Stony Brook University
10:40am - Quantitative imaging of Iodine-based contrast agent in dual-energy DBT - Emil Sidky, University of Chicago Medicine
Session 2 - DBT
Moderator: Ioannis Sechopoulos, Radboud University11:00am - Fast wide-angle DBT with high in-plane resolution – system concept and first clinical results - Ludwig Ritschl, Siemens Healthineers AG
11:20am - A YOLO-based learning lesion classifier of pre-exposure scan in digital breast tomosynthesis - Seoyoung Lee, KAIST
11:40am - Sample-efficient framework for breast lesion detection in Digital Breast Tomosynthesis: preliminary analysis on its generalizability - Belayat Hossain, University of Pittsburgh
12:00pm - Lunch
1:00pm - Poster Sessions
Moderators: Heather Whitney, University of Chicago and Hui Li, University of ChicagoPoster #1: Glandularity estimation in digital breast tomosynthesis with an accretion approach – Leonardo Coito Pereyra, Radboud University Medical Center
Poster #2: Local dynamic reconstruction in digital breast tomosynthesis – Matteo Barbieri, GE healthcare
Poster #3: Exploring Advanced 2D Acquisitions in Breast Tomosynthesis: T-shaped & Pentagon Geometries – Priyash Singh, University of Pennsylvania
Poster #4: When simulation becomes real: Exploring the characteristics of a 3D-printed power-law phantom in tomosynthesis imaging – Ingrid Reiser, University of Chicago
Poster #5: Evaluation of non-Gaussian statistical properties of digital breast tomosynthesis images – Kai Yang, Massachusetts General Hospital
Poster #6: Added value of feature uncertainty in a radiomic analysis of contrast-enhanced digital mammography boosted by deep learning – Robert Marti, University of Girona
Poster #7: Assessing the Feasibility of AI-Enhanced Portable Ultrasound for Improved Early Detection of Breast Cancer in Remote Areas – Nusrat Zaman Zemi – University of Hawaii Cancer Center
Poster #8: Comparing contemporary breast imaging technologies for use in dense-breast supplemental screening – Martin Tornai, Duke University Medical Center
Poster #9: Incorporating Longitudinal Screening Data into Image-Based Breast Cancer Risk Assessment – Tobias Wagner, KU Leuven
Poster #10: Recovering unprocessed digital mammograms from processed mammograms for quantitative analysis – Olivier Alonzo, Sunnybrook Health Sciences Center
Poster #11: Comparing percent breast density assessments of an AI-based method with expert reader estimates: inter-observer variability – Stepan Romanov, University of Manchester
Poster #12: Differences in Longitudinal Changes of Mammographic Breast Percent Density among Normal, Benign, and Cancer Patients: A Preliminary Study – Robert Nishikawa, University of Pittsburgh
Poster #13: The relationship between BMI, breast density, and cancer progression in breast cancer patients from Appalachian Kentucky – Braxton McFarland, University of Kentucky
Poster #14: Explainability of An AI-Based Breast Cancer Risk Prediction Tool – Sam Ellis, Royal Surrey NHS Foundation Trust
Poster #15: Accurate Estimation of Density and Background Parenchymal Enhancement in Breast MRI using Deep Regression and Transformers – Grey Kuling, Sunnybrook Research Institute
Poster #16: Regional Disparities in Visual Assessment of Breast Density: Implications for Risk Stratification in Breast Cancer Detection – Serena Pacile, Therapixel
Poster #17: Inter-manufacturer generalisation of AI on processed mammograms – Alistair Hickman, University of Surrey
Poster #18: How to go with that flow? A perfusion phantom for the optimization of dynamic contrast-enhanced dedicated breast CT – Liselot Goris, University of Twente
Poster #19: Survey of image processing used for mammography systems in the United Kingdom: how variable is it? – Alistair Mackenzie, Royal Surrey NHS Foundation Trust
Poster #20: Spatial analysis of immune cells in breast cancer using k-nearest neighbor graphs and Louvain-community clustering of immunofluorescent protein multiplexing images – Alison Cheung, Sunnybrook Research Institute
Poster #21: Sat2Nu: a modular deep learning pipeline for converting fat-suppressed breast MRIs to nonfat-suppressed images with foreseeable applications in abbreviated breast MRI – Nehal Doiphode, University of Pennsylvania
Poster #22: Adaptive thresholding technique for segmenting breast dense tissue in digital breast – Tamerlan Mustafaev, University of Pittsburgh Medical Center
Poster #23: Challenges with mammography of very thin breasts – John Loveland, Royal Surrey County Hospital
Poster #24: Evaluation of subtraction processing for mammograms analyzed by breast density and thickness – Chiharu Kai, Niigata University of Health and Welfare
Session 3 - Breast Cancer Screening
Moderator: Susan Astley, University of Manchester2:00pm - Further adventures in AI-directed double reading for single reading environments - Robert Nishikawa, University of Pittsburgh
2:20pm - Deep learning-based mammographic breast compression pressure estimates on processed images vs an unprocessed image reference - Melissa Hill, Volpara Health
2:40pm - Modelling the connection between image quality, cancer detection and overdiagnosis in breast imaging, a new perspective on DM and DBT - Magnus Dustler, Lund University
3:00pm - Break
Session 4 - Breast Density and Breast Cancer Risk
Moderator: Nico Karssemeijer, ScreenPoint Medical3:30pm - Breast composition measurements from full-field digital mammograms using generative adversarial networks - Eloy Garcia, Universitat de Girona
3:50pm - Longitudinal analysis of micro-calcifications features for breast cancer risk prediction with the Mirai model - Yao-Kuan Wang, UZ Leuven
4:10pm - Advancing Volumetric Breast Density Segmentation: A Deep Learning Approach with Digital Breast Tomosynthesis - Nehal Doiphode, University of Pennsylvania
4:30 - 5:30pm - Current Controversies Around Imaging-Based Dense-Breast Cancer Assessment Panel Discussion - Christine Edmonds, MD, John Shepherd, PhD, Chisako Muramatsu, PhD, Ioannis Sechopolous, PhD, Kirti Kulkarni, MD, Leslie Ferris Yerger, MBA
Moderator: Martin Tornai, NIH/NIBIBA tour of the Medical Imaging Labs will occur this evening. You will be able to sign up to participate in this tour onsite at the registration desk.
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7:30am - Registration and breakfast
8:30am - KEYNOTE: The Future of Molecular Imaging/Theranostics in Breast Cancer
- Christine E. Edmonds, MD, Hospital of the University of Pennsylvania
Moderators: Anders Tingberg, Lund University and Yulei Jiang, University of Chicago9:30am - Break
Session 5 - Devices and System Design
Moderator: Chisako Muramatsu, Shiga University10:00am - 4D dynamic contrast-enhanced breast CT: Evaluation of quantitative accuracy - Juan Pautasso, Radboud University Medical Center
10:20am - Cascaded System Analysis of a Direct-indirect Dual-layer Flat-panel-detector for Contrast-enhanced Breast Imaging - Xiangyi Wu, Stony Brook Medicine
10:40am - Breast cancer diagnosis using extended-wavelength diffuse reflectance spectroscopy – comparing tumor subgroups - Nadia Chaudhry, Lund University
Session 6 - Image Processing
Moderator: Despina Kontos, Columbia University11:00am - Asymmetric scatter kernel superposition-inspired deep learning approach to estimate scatter in digital breast tomosynthesis - Subong Hyun, KAIST
11:20am -Quantitative analysis of high-plex immunofluorescence microscopy images to investigate the breast cancer tumor microenvironment - Frederick Howard, University of Chicago
11:40am - Evaluating an image restoration pipeline for digital mammography across varied radiation exposures and microcalcification sizes using model observer analysis - Marcelo Andrade da Costa Vieira, University of São Paulo
12:00pm - Lunch
1:00pm - Poster Sessions
Moderators: Karen Drukker, University of Chicago and Ingrid Reiser, University of ChicagoPoster #26: Customizable digital mammography database: on-demand generation with user-defined radiation dose and microcalcification cluster characteristics – Marcelo Andrade da Costa Vieira, University of São Paulo
Poster #27: Creation of simulated mammography data to supplement machine learning training datasets – Anna Worthy, University of Surrey
Poster #28: Simulation of heterogeneity within breast lesions based upon Perlin noise – Hanna Tomic, Lund University
Poster #30: AI lesion risk score at different exposure settings – Anders Martin Tingberg, Skane University Hospital
Poster #31: Alignment of clinical breast tomosynthesis and mechanical images: The effect of the variation in shift and rotation – Predrag Bakic, Lund University
Poster #32: Characterization of invasive breast cancer lesions in breast x-ray imaging: a reference dataset for virtual imaging trials – Machteld Keupers, University Ziekenhuis Leuven
Poster #33: Measuring effective X-ray attenuation coefficients of 3D printing materials for anthropomorphic breast phantoms – Adrian Belarra, Universidad Complutense de Madrid
Poster #34: Noise measurements from a Quality Control programme tell a story – Kristina Tri Wigati, KU Leuven
Poster #35: The IAEA activities to support quality and safety in X ray breast imaging – Olivera Ciraj Bjelac, International Atomic Energy Agency
Poster #36: Evaluating the efficacy of automated breast arterial calcification quantification models in detecting BAC from mammograms with non-BAC calcifications – Kaier Wang, Volpara Health
Poster #37: SAM-PR: Enhancing 3D automated breast ultrasound imaging segmentation with probabilistic refinement of SAM – Robert Marti, University of Girona
Poster #38: Assessing the Impact of Counterfactuals for Textural Changes in Mammogram Classification – Ridhi Arora, University of Pittsburgh
Poster #39: 3D Breast Ultrasound Image Classification Using 2.5D Deep learning – Zhikai Yang, KTH Royal Institute of Technology
Poster #40: A Study on the Role of Radiomic Feature Stability in Predicting Breast Cancer Subtypes – Isabela Cama, Universita di Genova
Poster #41: Mitigating Annotation Shift in Cancer Classification Using Single Image Generative Models – Oliver Díaz, University of Barcelona
Poster #42: Exploring the possibility of extracting cancer morphology from deep feature cluster – Cory Thomas, Aberystwyth University
Poster #43: Automatic Detection of Breast Cancer Lumpectomy Margin from Intraoperative Specimen Mammography – Braxton McFarland, University of Kentucky
Poster #44: Slow-scan CE-DBT with focal spot steering – Priyash Singh, University of Pennsylvania
Poster #45: Localization, segmentation, and classification of mammographic abnormalities using deep learning – Reyer Zwiggelaar, Aberystwyth University
Poster #46: Segmentation and classification of mammographic abnormalities using local binary patterns and deep learning, Reyer Zwiggelaar, Aberystwyth University
Poster #47: Learning general cancer distribution: generalization of an AI model to diagnostic images – Serena Pacile, Therapixel
Poster #48: Time-to-event learning paradigm as a generalized approach to estimate risk of breast cancer using image based deep learning models – Serena Pacile, Therapixel
Session 7 - Virtual Clinical Trials
Moderator: Andrew Maidment, University of Pennsylvania2:00pm - Applicability of virtual breast phantoms for detectability studies in synthetic mammography - Katrien Houbrechts, KU Leuven
2:20pm - Use of microsimulation modeling for research in breast cancer screening - Martin Yaffe, Sunnybrook Research Institute
2:40pm - Adding tissue variability to digital breast phantoms for mammography and digital breast tomosynthesis simulations - Gustavo Pacheco, Radboud University Medical Center
3:00pm - Break
Session 8 - Multi-modality Imaging, Optical Imaging, and Dosimetry
Moderator: Hilde Bosmans, KU Leuven3:30pm - The added value of abbreviated MRI with UF DCE-MRI and DWI on digital breast tomosynthesis in diagnosing breast lesions - Akane Ohashi, Kyoto University Graduate School of Medicine
3:50pm - Developing ultrasound optical tomography for deep tissue imaging of the breast - Egle Bukarte, Lund University
4:10pm - Average glandular dose for contrast enhanced mammography examinations (CEM): a comparison between two centers - Najim Amallal EL Ouahabi, European University of Madrid
4:30 - 5:15pm - Role of Bias and Diversity in AI of Breast Cancer Imaging Panel Discussion -
Kristina Lång, MD, PhD, Karen Drukker, PhD, Ann-Katherine Carton, PhD, Andrew Maidment, PhD
Moderator: Heather Whitney, University of ChicagoThe 17th IWBI Gala and Dinner will take place tonight, from 6:30pm-9:30pm. Admission is included with your registration.
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7:30am - Registration and breakfast
8:30am - KEYNOTE: A breast radiologist’s perspective on AI - from experimental studies to randomized trials - Kristina Lång, MD, PhD, Lund University
Moderators: Elizabeth Krupinski, Emory University and Kirti Kulkarni, University of Chicago9:30am - Break
Session 9 - Artificial Intelligence in Breast Imaging I
Moderator: Robert Marti, University of Girona10:00am - Towards improved breast cancer detection on digital mammograms using local self-attention-based transformer - Han Chen/Anne Martel, Sunnybrook Research Institute
10:20am - Sureness of classification of breast cancers as pure DCIS or with invasive components on DCE-MRI - Heather Whitney, University of Chicago
10:40am - Longitudinal Interpretability of Deep Learning based Breast Cancer Risk Prediction model – Comparison of different Attribution Methods - Zan Klanecek, University of Ljubljana
Session 10 - Artificial Intelligence in Breast Imaging II
Moderator: Reyer Zwiggelaar, Aberystwyth University11:00am - Explainable radiomics to characterize breast density and tissue complexity: preliminary findings- Vincent Dong, University of Pennsylvania
11:20am -Deep-Learning based Background Parenchymal Enhancement Quantification in Contrast Enhanced Mammography: an application to Neoadjuvant Chemotherapy - Ann-Katherine Carton, GE HealthCare
11:40am - Improving the CNNs Performance of Mammography Mass Classification via Binary Mask Knowledge Transfer - Reyer Zwiggelaar, Aberystwyth University
12:00pm - Closing Remarks: Maryellen Giger, University of Chicago, Chair and boxed lunch
Meet our Keynote Speakers
Benjamin O. Anderson, MD, FACS
Global Technical Lead for Breast Cancer
City Cancer Challenge (C/Can), Geneva, Switzerland
Professor of Surgery and Global Health Medicine,
University of Washington
Christine E. Edmonds, MD
Assistant Professor of Radiology,
Hospital of the University of Pennsylvania
Olufunmilayo Olopade, MD, FACCR, OON
Walter L. Palmer Distinguished Service Professor of Medicine and Human Genetics
Associate Dean for Global Health
Director, Center for Clinical Cancer Genetics
University of Chicago
Kristina Lång, MD, PhD
Breast Radiologist and Clinical Researcher,
Lund University, Sweden
John A. Shepherd, PhD
Professor and Chief Scientific Officer,
University of Hawaii Cancer Center